Mortality Related Risk Factors in High-Risk Pulmonary Embolism in the ICU
Table 3
Admission clinical parameters of patients according to ESC classification (group 1: high-risk; group 2: intermediate- and low-risk).
Group 1
Group 2
value
Age (years)
72.0 (59.5–79.5)
68.0 (62.0–75.0)
0.493
Male gender
18 (43.9)
8 (53.3)
0.560
APACHE II score
18.0 (16.0–20.5)
18.0 (13.0–21.0)
0.243
Central PE in CTPA
35 (85.4)
11 (73.3)
0.431
Vital signs on admission
Heart rate (beats/min)
111.0 (100–120)
105.0 (95.0–121.0)
0.572
Systolic blood pressure (mmHg)
90.0 (85.0–100.0)
110.0 (100.0–120.0)
<0.001
Diastolic blood pressure (mmHg)
58.0 (51.5–64.0)
68.0 (60.0–70.0)
0.002
Breathing frequency (/min)
22 (20–25)
22.0 (18.0–24.0)
0.675
Shock index >
32 (78.0)
6 (40.0)
0.011
PA pressure (mmHg)
50.0 (45.0–60.0)
45.0 (40.0–55.0)
0.406
Arterial blood gas on admission
pH
7.43 (7.37–7.47)
7.48 (7.46–7.51)
0.003
PaCO2 (mmHg)
31.0 (27.2–35.9)
29.8 (23.7–35.5)
0.480
PaO2 (mmHg)
62.0 (48.0–81.7)
59.9 (47.6–67.2)
0.440
(mEq/L)
21.5 (18.3–23.5)
24.1 (19.5–26.2)
0.093
O2 saturation (%)
91.1 (84.2–97.0)
89.3 (81.3–94.0)
0.369
Lactate (mmol/L)
2.0 (1.1–3.3)
1.5 (1.1–2.1)
0.319
Troponin-T (ng/mL)
0.13 (0.05–0.73)
0.09 (0.05–0.47)
0.508
D-dimer (ng/mL)
7489 (2688–23476)
11000 (1807–16753)
0.627
Platelets (×103/mcL)
223.0 (168.5–321.5)
264.0 (180.0–350.0)
0.566
Invasive mechanical ventilation
15 (36.6)
1 (6.7)
0.043
Need for vasopressor therapy
28 (68.3)
0 (0.0)
<0.001
Thrombolytic therapy
29 (70.7)
4 (26.7)
0.005
Mortality
13 (31.7)
2 (13.3)
0.306
All values are expressed as numbers (percentages) or median (interquartile range). Shock index: heart rate/systolic blood pressure. Vasopressors used for sustaining blood pressure were either noradrenaline or dopamine. APACHE: acute physiology and chronic health evaluation; CTPA: computer tomography pulmonary angiography; PA: pulmonary artery; PaCO2: partial pressure of carbon dioxide; PaO2: partial pressure of oxygen; PE: pulmonary embolism.
