Effect of Continuous Positive Airway Pressure on Airway Inflammation and Oxidative Stress in Patients with Obstructive Sleep Apnea
Table 1
Demographic data in OSA patients pre- and post-CPAP therapy and non-OSA controls.
Non-OSA ()
Pre-CPAP ()
Post-CPAP ()
Age (years)
52.5 ± 12.3
53.1 ± 12.4
—
Gender (M/F)
10/3
10/3
10/3
BMI (kg/m2)
23.3 ± 1.5
28.4 ± 3.5##
28.1 ± 3.8
Neck circumference (cm)
36.9 ± 3.4
41.4 ± 2.6##
41.5 ± 3.4
Waist circumference (cm)
83.2 ± 5.7
102.7 ± 7.5###
101.8 ± 7.3
Hip circumference (cm)
92.8 ± 2.9
107.5 ± 9.4###
107.6 ± 8.7
Waist-to-hip ratio
0.90 ± 0.05
0.96 ± 0.05###
0.95 ± 0.04
Mean oxygen saturation (%)
98.2 ± 0.4
94.2 ± 4.7#
96.8 ± 1.3
Epworth sleepiness scale
2.9 ± 1.2
9.5 ± 2.9###
6.2 ± 1.8
Heart rate at rest (/min)
77 ± 10
77 ± 11
72 ± 8
Systolic BP (mm Hg)
123 ± 15
132 ± 12
124 ± 11
Diastolic BP (mm Hg)
75 ± 10
78 ± 6
74 ± 7
Mean arterial pressure (mm Hg)
90.9 ± 11.0
96.1 ± 7.3
90.6 ± 7.5
Controlled hypertension ()
0
9
9
Normotension ()
13
4
4
Data are expressed as mean ± SD. OSA: obstructive sleep apnea; CPAP: continuous positive airway pressure; BMI: body mass index; BP: blood pressure. , , and pre- versus post-CPAP therapy; , and non-OSA versus pre-CPAP therapy.
