Research Article

Pulmonary Hemodynamics and Six-Minute Walk Test Outcomes in Patients with Interstitial Lung Disease

Table 2

Pulmonary function, arterial gas analysis, hemodynamics, and 6 min walk test outcomes.

VariablesMean ± SDRange

Pulmonary function
 FVC, L2.3 ± 0.80.9–4.4
 FVC, % predicted76.7 ± 17.141.5–122.0
 DLco, mL/min/mmHg10.1 ± 3.24.8–17.0
 DLco, % predicted62.9 ± 16.037.8–118.1

Arterial gas analysis
 PaO2, mmHg76.6 ± 10.658.0–101.7
 PaCO2, mmHg40.6 ± 4.431.1–48.8
 pH7.41 ± 0.027.38–7.47

Hemodynamics
 Mean AP, mmHg91.3 ± 12.366.6–114.0
 RAP, mmHg2.9 ± 2.80.4–8.1
 Mean PAP, mmHg16.6 ± 4.87.0–27.0
 PCWP, mmHg6.5 ± 3.30–15.0
 CO, L/min4.7 ± 1.13.0–8.0
 Cardiac index, L/min/m23.0 ± 0.61.8–4.6
 PVR, dyne⋅s/cm5177 ± 810–342

6MWT outcomes
 Walk distance, m394 ± 102120–580
 SpO2 at end of the test, %85.4 ± 8.362–97
 Dyspnea at end of the test3.7 ± 2.60–10

The number of patients was 46 except for DLco which was 44 because 2 could not perform the examination for % DLco due to low pulmonary function.
Data are presented as mean ± standard deviation (SD). Dyspnea was assessed with the modified Borg scale.
FVC: forced vital capacity; DLco: diffusing capacity of carbon monoxide; PaO2: partial arterial pressure of oxygen; PaCO2: partial arterial pressure of carbon dioxide; AP: systemic arterial pressure; RAP: right arterial pressure; PAP: pulmonary artery pressure; PCWP: pulmonary capillary wedge pressure; CO: cardiac output; PVR: pulmonary vascular resistance; SpO2: transcutaneous oxygen saturation; 6MWT: 6 min walk test.