Canadian Respiratory Journal

Review Article

Noninvasive Positive Pressure Ventilation in Chronic Heart Failure

Table 2

Sensitivity analysis showing the effect sizes for the primary outcomes after removing individual trials included in the meta-analysis.
 LVEFOverall mortality
 MD [95% CI]P valueRR [95% CI]P value
All trialsRE: 5.34 [3.85, 6.82]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.89 [3.08, 4.69]<0.00001FE: 1.00 [0.96, 1.04]0.95
Naughton et al. 1995 omittedRE: 5.24 [3.72, 6.75]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.83 [3.02, 4.64]<0.00001FE: 1.00 [0.96, 1.04]0.95
Granton et al. 1996 omittedRE: 5.23 [3.73, 6.73]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.84 [3.03, 4.65]<0.00001FE: 1.00 [0.96, 1.04]0.95
Tkacova et al. 1997 omittedRE: 5.23 [3.72, 6.74]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.83 [3.02, 4.64]<0.00001FE: 1.00 [0.96, 1.04]0.95
Kaneko et al. 2003RE: 5.19 [3.67, 6.72]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.75 [2.93, 4.57]<0.00001FE: 1.00 [0.96, 1.04]0.95
Mansfield et al. 2004RE: 5.45 [3.90, 7.00]<0.00001RE: 1.01 [0.97, 1.04]0.74
FE: 3.89 [3.08, 4.70]<0.00001FE: 1.01 [0.97, 1.05]0.77
Bradley et al. 2005RE: 5.63 [4.25, 7.00]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 5.15 [4.14, 6.17]<0.00001FE: 1.00 [0.96, 1.03]0.86
Usui et al. 2005RE: 5.37 [3.85, 6.89]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.89 [3.08, 4.69]<0.00001FE: 1.00 [0.96, 1.04]0.95
Arzt et al. 2005RE: 5.55 [3.99, 7.12]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.94 [3.12, 4.76]<0.00001FE: 1.00 [0.96, 1.04]0.95
Egea et al. 2008RE: 5.64 [4.04, 7.24]<0.00001RE: 1.00 [0.96, 1.03]0.79
FE: 4.01 [3.17, 4.85]<0.00001FE: 1.00 [0.96, 1.04]0.96
Johnson et al. 2008RE: 5.43 [3.86, 7.00]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.87 [3.06, 4.69]<0.00001FE: 1.00 [0.96, 1.04]0.95
Ferrier et al. 2008RE: 5.45 [3.88, 7.01]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.88 [3.07, 4.70]<0.00001FE: 1.00 [0.96, 1.04]0.95
Pepperell et al. 2003RE: 5.50 [3.97, 7.03]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.92 [3.12, 4.73]<0.00001FE: 1.00 [0.96, 1.04]0.95
Koyama et al. 2010RE: 5.04 [3.58, 6.49]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.74 [2.92, 4.55]<0.00001FE: 1.00 [0.96, 1.04]0.95
Hastings et al. 2010RE: 5.09 [3.65, 6.54]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.80 [3.00, 4.61]<0.00001FE: 1.00 [0.96, 1.04]0.95
Oldenburg et al. 2011RE: 5.60 [3.91, 7.29]<0.00001RE: 1.00 [0.97, 1.04]0.79
FE: 3.90 [3.02, 4.79]<0.00001FE: 1.01 [0.96, 1.05]0.78
Koyama et al. 2011RE: 5.21 [3.67, 6.75]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.70 [2.87, 4.53]<0.00001FE: 1.00 [0.96, 1.04]0.95
Haruki et al. 2011RE: 5.23 [3.71, 6.74]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.82 [3.01, 4.63]<0.00001FE: 1.00 [0.96, 1.04]0.95
Yoshihisa et al. 2011RE: 5.33 [3.79, 6.88]<0.00001RE: 1.00 [0.97, 1.03]0.86
FE: 3.84 [3.03, 4.65]<0.00001FE: 1.00 [0.96, 1.04]0.87
Joho et al. 2012RE: 4.95 [3.52, 6.38]<0.00001RE: 1.00 [0.97, 1.03]0.98
FE: 3.69 [2.87, 4.50]<0.00001FE: 1.00 [0.96, 1.04]0.95
LVEF: left ventricular ejection fraction; MD: mean difference; RR: risk ratio; RE: random effect model; FE: fixed effect model.