Research Article
EGFR Mutation Analysis of Circulating Tumor DNA Using an Improved PNA-LNA PCR Clamp Method
Table 3
Detection of EGFR mutations from tissue and plasma samples.
| | (%) | Tissue | Plasma | Tissue | | Before treatment | Before treatment
P0 (%) | Under treatment
P1 (%) | After PD
P2 (%) | After PD |
| | Number of samples | 24 | 24 | 23 | 16 | 3 | | Activating mutation | 24 | 19 (79.2) | 6 (26.1) | 11 (68.8) | 3 (100) | | Drug-resistant mutation (T790M) | NA | 2 (8.3) | 4 (17.4) | 8 (50.0) | 3 (100) |
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