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Canadian Respiratory Journal
Volume 2016 (2016), Article ID 5624315, 7 pages
http://dx.doi.org/10.1155/2016/5624315
Clinical Study

Effects of Lung Expansion Therapy on Lung Function in Patients with Prolonged Mechanical Ventilation

1Department of Respiratory Care, Chang Gung University College of Medicine, 259 Wenhua 1st Road, Guishan District, Taoyuan City 33302, Taiwan
2Department of Respiratory Therapy, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fu-Shing Street, Guishan District, Taoyuan City 33305, Taiwan
3Department of Thoracic Medicine, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, 5 Fu-Shing Street, Guishan District, Taoyuan City 33305, Taiwan

Received 10 May 2015; Accepted 15 September 2015

Copyright © 2016 Yen-Huey Chen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Common complications in PMV include changes in the airway clearance mechanism, pulmonary function, and respiratory muscle strength, as well as chest radiological changes such as atelectasis. Lung expansion therapy which includes IPPB and PEEP prevents and treats pulmonary atelectasis and improves lung compliance. Our study presented that patients with PMV have improvements in lung volume and oxygenation after receiving IPPB therapy. The combination of IPPB and PEEP therapy also results in increase in respiratory muscle strength. The application of IPPB facilitates the homogeneous gas distribution in the lung and results in recruitment of collapsed alveoli. PEEP therapy may reduce risk of respiratory muscle fatigue by preventing premature airway collapse during expiration. The physiologic effects of IPPB and PEEP may result in enhancement of pulmonary function and thus increase the possibility of successful weaning from mechanical ventilator during weaning process. For patients with PMV who were under the risk of atelectasis, the application of IPPB may be considered as a supplement therapy for the enhancement of weaning outcome during their stay in the hospital.