Table 2: BAL pepsin in wheezy infants based on the presence of GERD compared to healthy control.

Group 1Group 2Group 3Group 4Group 5Control

13218104210
Pepsin (mean ± SD)36.5 ± 7.845.3 ± 8.642.8 ± 837.9 ± 6.842.1 ± 8.329 ± 2.6<0.0001

Group 1: typical GERD symptoms present and combined MII-pH positive, Group 2: typical GERD symptoms absent and combined MII-pH positive, Group 3: typical GERD symptoms present and combined MII-pH negative, Group 4: typical GERD symptoms absent and combined MII-pH negative, and Group 5: GERD symptoms and/or combined pH-MII positive. Similar letters indicate significance between groups; A ( < 0.0001), B ( = 0.011), and C ( < 0.0001).