Clinical Utility of Bronchoalveolar Lavage Pepsin in Diagnosis of Gastroesophageal Reflux among Wheezy Infants

Table 2

BAL pepsin in wheezy infants based on the presence of GERD compared to healthy control.

	Group 1	Group 2	Group 3	Group 4	Group 5	Control
	13	21	8	10	42	10
Pepsin (mean ± SD)	36.5 ± 7.8	45.3 ± 8.6	42.8 ± 8	37.9 ± 6.8	42.1 ± 8.3	29 ± 2.6	<0.0001

Group 1: typical GERD symptoms present and combined MII-pH positive, Group 2: typical GERD symptoms absent and combined MII-pH positive, Group 3: typical GERD symptoms present and combined MII-pH negative, Group 4: typical GERD symptoms absent and combined MII-pH negative, and Group 5: GERD symptoms and/or combined pH-MII positive. Similar letters indicate significance between groups; A ( < 0.0001), B ( = 0.011), and C ( < 0.0001).