Clinical Utility of Bronchoalveolar Lavage Pepsin in Diagnosis of Gastroesophageal Reflux among Wheezy Infants

Table 3

Bronchoalveolar fluid pepsin correlation with MII-pH monitoring parameters.

⁢BAL pepsin
	Below one year		1-2 years
	pH monitoring parameters
Number of acid reflux episodes	0.03	0.858		0.84
Reflux index	0.06	0.71	0.409	0.146
Mean acid clearance time	0.02	0.906	0.745	0.002
Longest acid episode	0.101	0.546	0.587	0.02
Acid episodes longer than 5 minutes	0.005	0.97	0.47	0.08
MII parameters
Acid percent time	0.08	0.634		0.244
Nonacid percent time	0.098	0.558		0.89
Bolus exposure index	−0.055	0.741		0.75
Median bolus clearance time	−0.321	0.05		0.29
Longest impedance episode	0.026	0.879		0.88
Number of distal acid reflux episodes	0.037	0.825	0.006	0.985
Number of distal nonacid reflux episodes	0.135	0.419		0.496
Number of all distal reflux episodes	0.091	0.588		0.764
Number of proximal acid reflux episodes		0.863		0.584
Number of proximal nonacid reflux number episodes	0.094	0.574		0.612
Number of all proximal reflux episodes	0.014	0.934		0.61

BAL pepsin correlates with mean acid clearance time and the longest acid episode.