Research Article
Clinical Utility of Bronchoalveolar Lavage Pepsin in Diagnosis of Gastroesophageal Reflux among Wheezy Infants
Table 3
Bronchoalveolar fluid pepsin correlation with MII-pH monitoring parameters.
| BAL pepsin | | Below one year | 1-2 years | | | | |
| pH monitoring parameters | | | | | Number of acid reflux episodes | 0.03 | 0.858 | | 0.84 | Reflux index | 0.06 | 0.71 | 0.409 | 0.146 | Mean acid clearance time | 0.02 | 0.906 | 0.745 | 0.002 | Longest acid episode | 0.101 | 0.546 | 0.587 | 0.02 | Acid episodes longer than 5 minutes | 0.005 | 0.97 | 0.47 | 0.08 |
| MII parameters | | | | | Acid percent time | 0.08 | 0.634 | | 0.244 | Nonacid percent time | 0.098 | 0.558 | | 0.89 | Bolus exposure index | −0.055 | 0.741 | | 0.75 | Median bolus clearance time | −0.321 | 0.05 | | 0.29 | Longest impedance episode | 0.026 | 0.879 | | 0.88 | Number of distal acid reflux episodes | 0.037 | 0.825 | 0.006 | 0.985 | Number of distal nonacid reflux episodes | 0.135 | 0.419 | | 0.496 | Number of all distal reflux episodes | 0.091 | 0.588 | | 0.764 | Number of proximal acid reflux episodes | | 0.863 | | 0.584 | Number of proximal nonacid reflux number episodes | 0.094 | 0.574 | | 0.612 | Number of all proximal reflux episodes | 0.014 | 0.934 | | 0.61 |
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BAL pepsin correlates with mean acid clearance time and the longest acid episode.
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