Research Article

Clinical Utility of Bronchoalveolar Lavage Pepsin in Diagnosis of Gastroesophageal Reflux among Wheezy Infants

Table 4

Relation between BAL pepsin and GERD diagnostic tests.

Normal pepsin (%)Abnormal pepsin (%)
23 (44.2)29 (55.8)

Combined
MII-pH
+ve13 (56.5)21 (72.4)0.23
−ve10 (43.5)8 (27.6)

Reflux
esophagitis
+ve5 (21.7)13 (44.8)0.14
−ve18 (78.3)16 (55.2)

LLMI≥1006 (26.1)14 (48.3)0.15
10017 (73.9)15 (51.7)

LLMI, lipid laden macrophage index; MII-pH, multiple intraluminal impedance-pH monitoring. No significant relation occurs between abnormal BAL pepsin and abnormal combined MII-pH, reflux esophagitis, and LLMI ≥ 100.