The Effect of the Treatment with Heated Humidified High-Flow Nasal Cannula on Neonatal Respiratory Distress Syndrome in China: A Single-Center Experience

Table 1

Demographic characteristics of the study population.

Characteristic	HHHFNC ()	NCPAP ()
Gestational age, week, mean (SD)	31.9 (1.7)	31.9 (1.8)
<32 weeks, (%)	20 (30.8)	22 (34.9)
Birth weight, mean ± SD, g	1754 (299)	1790 (373)
<1500 g, (%)	16 (24.6)	16 (25.4)
Small for gestational age, number (%)	3 (4.6)	4 (6.3)
Female, number (%)	35 (53.8)	30 (47.6)
Multiple birth, number (%)	14 (21.5)	16 (25.4)
Antenatal steroids, number (%)	26 (40)	23 (36.5)
Cesarean delivery, number (%)	35 (53.8)	31 (49.2)
Neonatal resuscitation, number (%)	38 (58.5)	35 (55.6)
Apgar score at 5 min, median (IQR)	9 (8-9)	9 (8-9)
Prestudy surfactant, (%)	20 (30.8)	22 (34.9)
Prestudy caffeine, (%)	24 (36.9)	25 (39.7)
pH before enrollment, mean (SD)	7.19 (0.06)	7.19 (0.06)
before enrollment, mean (SD), mmHg	55.3 (3.3)	55.5 (3.5)
before enrollment, median (IQR)	0.23 (0.21–0.30)	0.25 (0.21–0.30)

, fraction of inspired oxygen; HHHFNC, heated, humidified high-flow nasal cannula; IQR, interquartile range; NCPAP, nasal continuous positive airway pressure; , partial pressure of carbon dioxide.
for all comparisons.