The Effect of the Treatment with Heated Humidified High-Flow Nasal Cannula on Neonatal Respiratory Distress Syndrome in China: A Single-Center Experience

Table 4

Occurrence rates for secondary outcomes in the HHHFNC compared with the NCPAP study group.

Outcome	HHHFNC ()	NCPAP ()	95% CI of risk difference	value
Adverse event, number (%)
Confirmed sepsis	5 (7.7)	7 (11.1)	0.20 to 2.22	0.51
IVH	3 (4.6)	2 (3.2)	0.24 to 9.14	0.67
PDA	4 (6.2)	4 (6.3)	0.23 to 4.05	0.96
ROP	3 (4.6)	2 (3.2)	0.24 to 9.14	0.67
nasal trauma	14 (21.5)	27 (42.9)	0.17 to 0.79	0.01
Death	1 (1.5)	1 (1.6)	0.06 to 16.08	0.99
Abdominal distention	7 (10.8)	8 (12.7)	0.28 to 2.44	0.73
Days to full oral feedings, median (IQR), d	11.1 (5–20)	11.5 (5–24)	−2.30 to 1.50	0.68
Exclusive breastfeeding at discharge, number (%)	12 (18.5)	10 (15.9)	0.48 to 3.02	0.70
Weight at discharge, median (IQR), g	2150 (2000 to 2450)	2176 (2050 to 2550)	−73.5 to 22.5	0.30