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Canadian Respiratory Journal
Volume 2017, Article ID 4521302, 9 pages
Research Article

Burden of Respiratory Syncytial Virus Hospitalizations in Canada

1Alberta Children’s Hospital, 2888 Shaganappi Trail NW, Calgary, AB, Canada T6B 6A8
2AbbVie Corporation, 8401 Trans-Canada Highway, Saint-Laurent, QC, Canada H4S 1Z1
3AbbVie, Inc., 1 N. Waukegan Road, North Chicago, IL 60064, USA

Correspondence should be addressed to ElizaBeth Grubb; moc.eivbba@bburg.htebazile

Received 16 May 2017; Revised 18 September 2017; Accepted 10 October 2017; Published 7 November 2017

Academic Editor: Christophe Leroyer

Copyright © 2017 Ian Mitchell et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To examine the socioeconomic burden of respiratory syncytial virus (RSV) disease for Canadian infants hospitalized for the condition. Data and Methods. The descriptive study used data collected in Alberta, Canada, during 2 consecutive RSV seasons. Infants (<1 year of age) were included if they had not received palivizumab and were hospitalized with a confirmed diagnosis of RSV. Hospitalization resource use and parental time burden, out-of-pocket costs, lost work productivity, and stress and anxiety were assessed. Results. 13.4% of all infants (n = 67) had intensive care unit (ICU) admission, and average ICU stay for these infants was 6.5 days. Families had average out-of-pocket expenses of 736.69 Canadian dollars (CAD $), and the average time both parents spent in hospital was nearly 7 days (164.0 hours). For working parents (n = 43), average absenteeism was 49% and overall work impairment was 77.8%. Parents also exhibited significant parental stress (3.6 on the Parental Stressor Scale: 43.9 state anxiety and 36.9 trait anxiety scores). Conclusions. Results indicate a high burden associated with the hospitalization of an infant due to RSV disease in terms of resource use, time, productivity, costs, and stress, even among a population of infants not considered to be at risk for the condition.