The Effect of Mechanical Ventilation on TASK-1 Expression in the Brain in a Rat Model

Figure 1

Hemodynamic and respiratory characteristics of rats during the four-hour period of ventilation. No differences between groups were observed at baseline. MAP remained stable in both groups. There were no differences between the LVt and HVt for arterial oxygen saturation (SaO₂). PaCO₂ in LVt animals was higher than in HVt animals. The pH decreased slightly in the HVt animals at four hours. But neither PaCO₂ nor pH had significant difference between two ventilatory groups during 4-hour period. Data are presented as the mean ± SD. animals per group. MAP, mean arterial pressure; BAS, basal; LVt, low tidal volume; HVt, high tidal volume; SaO₂, arterial oxygen saturation; PaCO₂, partial pressure of carbon dioxide in arterial blood.