The Role of Serotonin Transporter in Human Lung Development and in Neonatal Lung Disorders

Figure 2

Expression of SERT in the pulmonary endothelium during development (3,3′-diaminobenzidine, SERT antibody expression in brown). (a) At 16 WGA (pseudoglandular stage); no SERT expression is detected (400x). (b) At 28 WGA (canalicular stage) no SERT expression is detected (400x). (c) At 30 WGA (saccular stage) patchy capillary SERT staining (arrows) is detected (400x). (d) At 37 WGA (alveolar stage) diffuse and intense microvascular staining of SERT (arrows) is evident (400x). (e) At one year of age SERT staining (arrows) is diffuse and intense (400x). (f) At 10 years of age SERT staining (arrows) remains diffusely present (400x).

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