Canadian Respiratory Journal

Research Article

Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease

Table 1

Characteristics of patients.


Characteristic	Clubbing (−)	Clubbing (+)	value
Characteristic	n = 85	n = 17	value

Age, years	70.9 ± 12.87	64.2 ± 13.6	0.06
Male sex, number	48 (65)	9 (64)	0.79
Pack-years	26.4 ± 29.2	28.2 ± 40.5	0.83
sPAP, mmHg^†	30.9 ± 13.0	33.8 ± 14.6	0.49
LVEF, %^†	62.0 ± 9.7	60.5 ± 9.5	0.61
HRCT imaging patterns
NSIP	47 (55.3%)	10 (58.8%)	1.00
UIP	12 (14.1%)	2 (11.8%)	1.00
OP	3 (3.5%)	0 (0%)	1.00
Pattern not specified	23 (27.1%)	5 (29.4%)	0.84

Note. Data are means ± standard deviation or number (%); sPAP = systolic pulmonary arterial pressure; LVEF = left ventricular ejection fraction; ^†data were missing for 33 patients in the clubbing (−) group and four patients in the clubbing (+) group for sPAP and 24 patients in the clubbing (−) group and three patients in the clubbing (+) group for LVEF.