Research Article
Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease
Table 2
Diagnostic category of participants.
| | Diagnostic category | Clubbing (−) | Clubbing (+) | value | Prevalence of clubbing | | n = 85 | n = 17 |
| | CTD-ILD | 44 (51.8%) | 6 (35.3%) | 0.29 | 12.0% | | RA-ILD | 14 (16.5%) | 1 (5.9%) | 0.46 | 6.7% | | NSIP pattern | 7 | 1 | — | — | | UIP pattern | 3 | 0 | — | — | | Pattern not specified | 4 | 0 | — | — | | DM-ILD | 12 (14.1%) | 0 (0%) | 1 | 0.0% | | NSIP pattern | 12 | 0 | — | — | | SSc-ILD | 15 (17.6%) | 5 (29.4%) | 0.32 | 25.0% | | NSIP pattern | 8 | 4 | — | — | | UIP pattern | 1 | 0 | — | — | | OP pattern | 1 | 0 | — | — | | Pattern not specified | 5 | 1 | — | — | | SS-ILD | 3 (3.5%) | 0 (0%) | 1 | 0.0% | | NSIP pattern | 1 | 0 | — | — | | UIP pattern | 1 | 0 | — | — | | OP pattern | 1 | 0 | — | — | | Non-CTD-ILD | 41 (48.2%) | 11 (64.7%) | 0.29 | 21.1% | | NSIP pattern | 19 (22.4%) | 5 (29.4%) | 0.54 | 20.8% | | HP suspected | 1 | 1 | — | — | | IIP | 0 | 1 | — | — | | UIP pattern | 7 (8.2%) | 2 (11.8%) | 0.64 | 22.2% | | HP suspected | 1 | 0 | — | — | | OP pattern | 1 (1.2%) | 0 (0%) | 1 | 0.0% | | Pattern not specified | 14 (16.5%) | 4 (23.5%) | 0.49 | 22.2% |
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CTD-ILD = connective tissue disease-associated interstitial lung disease; RA = rheumatoid arthritis; NSIP = nonspecific interstitial pneumonia; UIP = usual interstitial pneumonia; DM = dermatomyositis; SSc = systemic sclerosis; OP = organizing pneumonia; SS = Sjogren’s disease; HP = hypersensitivity pneumonia; IIP = idiopathic interstitial pneumonia.
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