Pretreatment Hemoglobin Level Is an Independent Prognostic Factor in Patients with Lung Adenocarcinoma

Table 3

Multivariate analysis of prognostic factors for patients with lung adenocarcinoma in Henan, China, 2017.

Factor	HR^1	95% CI^2	value
Age
<65	1.00
≥65	1.20	0.90–1.60	0.211
Sex
Man	1.00
Women	0.89	0.66–1.19	0.432
TNM^3 stage
I–III	1.00
IV	1.39	0.98–1.99	0.067
KPS^4 scores
≥80	1.00
<80	1.24	0.93–1.64	0.139
Lung lobectomy
Yes	1.00
No	2.01	1.32–3.05	0.001
Chemotherapy
Yes	1.00
No	1.47	1.10–1.95	0.008
Radiotherapy
Yes	1.00
No	1.00	0.68–1.49	0.981
Alcohol drinking
No	1.00
Yes	1.60	1.06–2.41	0.026
Hemoglobin^5
NPHb	1.00
LPHb	1.48	1.06–2.08	0.023

¹HR: hazard ratio by multivariate Cox proportional hazards regression. ²CI: confidence interval. ³TNM: tumor-node-metastasis. ⁴KPS: Karnofsky performance status. ⁵Hemoglobin: NPHb (normal pretreatment hemoglobin): men 120–160 g/l and women 110–150 g/l; LPHb (low pretreatment hemoglobin): men < 120 g/l and women ≤ 110 g/l.