Research Article

Daily Chronic Intermittent Hypobaric Hypoxia Does Not Induce Chronic Increase in Pulmonary Arterial Pressure Assessed by Echocardiography

Table 1

Baseline characteristics.

Matched characteristicsCIHHControls value

Total subject number, n88
Female, n44
Age, years median (min; max)34 (29; 50)34.5 (28; 51)
BMI, kg/m2 (±SD)25.30 ± 3.7823.90 ± 6.190.57
Smoking (current/ex/never)2/2/40/1/70.21
Packyears
 Current8; 16
 Ex-smoker0.5; 212
Endurance sport activity (regular/sometimes/rarely)2/6/02/5/10.58
Treated hypertension, n22
Treated hypothyreosis, n01>0.99
Duration of CIHH, years
 (i) Median (min; max)3.7 (2.5; 20)
 (ii) Individual values2.5, 3, 3.2, 3.4, 4, 5, 10, 20

CIHH: chronic intermittent hypobaric hypoxia; by t-test or chi-square test as appropriate. Endurance physical activity was defined as cardiac workout of at least 30 min: regular >1/week; sometimes 1–3x/month; rarely <1/month.