Canadian Respiratory Journal

Research Article

Endocan, a Risk Factor for Developing Acute Respiratory Distress Syndrome among Severe Pneumonia Patients

Table 3

Risk factors for ARDS development by univariate and multiple logistic regression analysis in SP patients.


Parameters	Univariate/multivariate			value
Parameters	OR (95% CI)	value	OR (95% CI)	value

Age	1.04 (0.83–1.36)	0.61
SOFA score	0.85 (0.62–1.25)	0.42
LIS	1.24 (0.91–1.78)	0.17
Body temperature	1.12 (0.78–1.59)	0.52
Heart rate	1.47 (1.03–2.13)	0.021	0.99 (0.73–1.41)	0.75
SBP	1.22 (0.85–1.79)	0.25
SpO₂	1.03 (0.81–1.38)	0.77
BUN	1.17 (0.73–1.65)	0.61
Creatinine	1.04 (0.73–1.45)	0.082	1.17 (0.72–1.88)	0.65
Lactate	0.73 (0.53–0.99)	0.018	1.03 (0.66–1.57)	0.51
Endocan	1.65 (1.18–2.42)	0.012	1.57 (1.14–2.25)	0.021
CRP	1.21 (0.98–1.57)	0.067	1.22 (0.95–1.68)	0.17
PaO₂/FiO₂	1.86 (1.17–3.12)	0.024	1.57 (0.79–2.81)	0.14

SP, severe pneumonia; ARDS, acute respiratory distress syndrome; SOFA, sequential organ failure assessment; LIS, lung injury score; SBP, systolic blood pressure; SpO₂, oxygen saturation of pulse oximetry; BUN, blood urea nitrogen; CRP, C-reactive protein; PaO₂/FiO₂, ratio of partial pressure of arterial oxygen to fraction of inspired oxygen; CI, confidence interval; OR, odds ratio. .