Clinical Features and Contributing Factors of Excessive Daytime Sleepiness in Chinese Obstructive Sleep Apnea Patients: The Role of Comorbid Symptoms and Polysomnographic Variables
Table 3
PSG variables of the total OSA patients and the patients with different severities of EDS.
Total
Non-EDS
Mild to moderate EDS
Severe EDS
F
p
Sleep efficiency (%)
84.8 ± 12.3
83.5 ± 12.9
87.3 ± 10.3c
88.2 ± 10.3a
11.032
<0.0001
WASO (min)
49.0 ± 49.3
52.6 ± 52.8
43.9 ± 41.0c
34.8 ± 39.5a
5.537
0.004
SL (min)
28.7 ± 27.2
31.0 ± 27.6
26.4 ± 27.7
16.1 ± 14.4a,b
10.119
<0.0001
N1 (%)
42.7 ± 19.2
40.7 ± 17.3
46.4 ± 22.6c
48.5 ± 19.5a
10.775
<0.0001
N2 (%)
44.6 ± 14.7
45.5 ± 14.2
43.5 ± 15.3
40.3 ± 16.7a
4.405
0.012
N3 (%)
4.2 ± 6.4
4.6 ± 6.6
3.1 ± 5.1c
4.6 ± 7.3
4.867
0.008
REM (%)
8.7 ± 6.2
9.2 ± 6.2
7.9 ± 5.8c
6.6 ± 6.0a
7.922
<0.0001
MAI (h−1)
44.4 ± 20.6
40.8 ± 19.4
51.5 ± 20.7c
51.4 ± 22.9a
27.643
<0.0001
AHI (h−1)
46.7 ± 24.7
36.6 ± 23.2
54.4 ± 22.8c
55.7 ± 24.7a
58.831
<0.0001
TAmax (s)
60.2 ± 27.3
56.2 ± 25.7
68.7 ± 28.7c
66.1 ± 28.5a
19.781
<0.0001
Nadir SpO2
71.8 ± 13.4
74.7 ± 11.3
66.5 ± 15.1c
64.6 ± 15.3a
45.422
<0.0001
Mean SpO2
92.9 ± 3.4
93.7 ± 2.6
91.7 ± 4.0c
90.4 ± 5.2a
50.413
<0.0001
ODI (h−1)
43.1 ± 25.8
36.9 ± 24.1
54.8 ± 24.3c
57.2 ± 26.2a
55.829
<0.0001
SIT90 (%)
16.0 ± 22.9
12.3 ± 16.6
22.6 ± 32.4c
26.5 ± 23.5a
25.205
<0.0001
Data are presented as mean ± SD. aComparisons between non-EDS versus severe EDS groups ();bcomparisons between mild to moderate EDS versus severe EDS groups ();ccomparisons between non-EDS versus mild to moderate EDS groups (). EDS: excessive daytime sleepiness; WASO: wake after sleep onset; SL: sleep latency; REM: rapid eye movement; MAI: microarousal index; AHI: apnea-hypopnea index; TAmax: the longest time of apnea; ODI: oxygen desaturation index; SIT90: saturation impair time below 90%.