Research Article
MIP-T3 Expression Associated with Defects of Ciliogenesis in Airway of COPD Patients
| | Nonsmoker group | Healthy smoker group | COPD smoker |
| Total of subjects (n) | 21 | 17 | 18 | Sex (male, n (%)) | 18 (85.71) | 16 (94.11) | 17 (94.44) | Age (year, mean ± SD) | 58.57 ± 11.23 | 57.35 ± 10.40 | 62.22 ± 9.40 | Smoking index (pack years, mean ± SD) | | 28.91 ± 18.49 | 46.37 ± 17.66 | Disease constitution carcinoma, n (%) | 19 (90.47) | 16 (94.11) | 17 (94.44) | FEV1(L, mean ± SD) | 2.30 ± 0.78 | 2.69 ± 0.63 | 1.79 ± 0.47 | FVC (L, mean ± SD) | 2.97 ± 0.98 | 3.58 ± 0.87 | 3.04 ± 0.51 | FVC%pred (mean ± SD) | 84.24 ± 6.62 | 86.74 ± 7.01 | 81.52 ± 5.22 | FEV1/FVC (mean ± SD) | 78.29 ± 6.78 | 75.53 ± 8.10 | 58.33 ± 10.23 | FEV1%pred (mean ± SD) | 96.76 ± 10.10 | 94.12 ± 12.92 | 65.89 ± 15.44 |
|
|
FEV 1: forced expiratory volume in the first second; FVC: forced vital capacity. vs nonsmoker group, value <0.05. vs healthy smoker group, value <0.05. |