Research Article
Clinical Features and Risk Factors for Mortality in Hospitalized Older Adults with Pneumonia
| | Vaccinated | Unvaccinated | value | n = 38 (%) | n = 55 (%) |
| Demographics | | | | Age, median (IQR) | 81 (74–84) | 80 (71–87) | 0.94 | Males | 23 (60.5) | 31 (56.3) | 0.69 | Females | 15 (39.5) | 24 (43.6) | 0.69 | PS, median (IQR) | 1 (0–2) | 1 (0–3) | 0.25 | HCAP | 4 (10.5) | 13 (23.6) | 0.10 | Vaccination against influenza | 33 (86.8) | 15 (27.3) | <0.001 |
| Comorbid conditions | | | | Hypertension | 12 (31.6) | 18 (32.8) | 0.91 | Diabetes | 6 (15.8) | 7 (12.7) | 0.68 | Heart disease | 15 (39.5) | 13 (23.6) | 0.1 | Kidney disease | 3 (7.9) | 7 (12.7) | 0.46 | Neurological disease | 6 (15.8) | 13 (23.6) | 0.36 | Cancer | 7 (18.4) | 5 (9.1) | 0.19 | Respiratory disease | 26 (68.4) | 27 (49.1) | 0.06 |
| Types of pneumococcal vaccine | | | | PPV23 | 27 (71.1) | | | PCV13 | 2 (5.2) | | | PPV23 + PCV13 | 1 (2.6) | | | Unknown | 8 (21.1) | | |
| Time after PPV23 vaccination | | | | <5 years | 21 (75.0) | | | >5 years | 6 (21.4) | | | Unknown | 1 (2.6) | | |
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IQR: interquartile range; PS: performance status; HCAP: healthcare-associated pneumonia; PPV23: 23-valent pneumococcal polysaccharide vaccine; PCV13: 13-valent pneumococcal conjugate vaccine.
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