Temporal Associations of the SARS-CoV-2 NP Antigen and Anti-Spike Total Ig Levels with Laboratory Parameters in a Greek Cohort of Hospitalized COVID-19 Patients
Table 2
Descriptive statistics of the SARS-CoV-2 and host-associated variables that were serially measured in this study.
Mean ± std. error of mean
valuesV
Mild-moderate cases
Severe-critical cases
Ag (A.U.)
166.63 ± 52.85
43.51 ± 15.98
0.002
Total Ig (A.U.)
6.98 ± 1.02
9.51 ± 0.51
0.011
White blood cells (number/mm3)
8263.27 ± 479.54
8592.37 ± 259.11
ns
Neutrophils (number/mm3)
6410.41 ± 423.51
6593.36 ± 251.32
ns
Lymphocytes (number/mm3)
1193.47 ± 88.14
1136.34 ± 54.61
ns
Platelets (number/mm3)
297265.31 ± 17308.34
295992.37 ± 10156.99
ns
Ferritin (ng/ml)
539.77 ± 153.76
948.17 ± 103.89
<0.001
C-reactive protein (mg/dl)
2.85 ± 0.78
3.18 ± 0.31
0.040
D-dimer (ng/ml)
392.06 ± 37.14
417.82 ± 23.78
ns
Lactate dehydrogenase (U/L)
249.06 ± 10.69
267.20 ± 8.26
ns
Lactic acid (mmol/L)
0.87 ± 0.04
0.92 ± 0.02
ns
Urea (mg/dl)
38.74 ± 2.23
46.48 ± 1.74
0.005
Creatinine (mg/dl)
0.78 ± 0.03
0.89 ± 0.03
ns
Alanine transaminase (U/L)
80.78 ± 32.76
51.28 ± 3.43
0.004
Mann–Whitney U test; the mean ranks for Ag, total Ig, ferritin, C-reactive protein, urea, and ALT in mild-moderate cases were 105.43; 74.42; 57.50; 77.43; 72.84; and 72.29 versus 84.92; 96.52; 102.84; 95.39; 97.11; and 97.31 in severe-critical cases, respectively.
