Blood Eosinophils and Pulmonary Rehabilitation in COPD

Table 2

Within-group change on outcomes postpulmonary rehabilitation.

Outcome	Eosinophils	Baseline, mean	Post-PR, mean	Mean difference (95% CI)	value
BODE index	≥300	5.83	4.58	−1.25 (−0.45, −4.25)	<0.001
	<300	5.50	4.17	−1.33 (−1.72, −0.94)	<0.001
6MWT (m)	≥300	240.3	269.5	29.2 (14.2, 44.4)	<0.001
	<300	250.4	365.5	115.1 (−30.4, 260.6)	0.12
FEV1 (%)	≥300	35.6	35.0	−0.6 (−2.64, 1.48)	0.58
	<300	36.8	39.3	2.5 (0.77, 4.17)	0.005
			No improvement (%)	Improved (%)
mMRC scale	≥300		86.6	13.3	n/a
	<300		86.0	14.0	n/a

PR, pulmonary rehabilitation; CI, confidence interval; BODE, body mass index, airflow obstruction, dyspnea, and exercise capacity; 6MWT, 6-minute walk test; m, meters; FEV1, forced expiratory volume in 1 second; mMRC, modified Medical Research Council; n/a, not applicable. mMRC change measured as a proportion (%).