Research Article

The Extent of Honeycombing on Computed Tomography Cannot Predict the Treatment Outcome of Patients with Acute Exacerbations of Interstitial Lung Disease

Table 4

Univariate and multivariate analysis of primary predictors of 3-month mortality.

VariableUnivariatesMultivariates
Odds ratio95% CIOdds ratio95% CI

Honeycomb present
Age1.0670.912–1.0870.918
Sex5.3480.629–45.4790.125
CCIS1.4940.970–1.6520.082
Diagnosis of ILDs0.5890.124–2.7970.505
Serum LDH1.0051.002–1.0080.0051.0051.002–1.007<0.001
Serum KL-61.0001.000–1.0010.454
P/F ratio0.9980.990–1.0060.580
GGO score0.8860.723–1.0850.244

Honeycomb absent
Age1.0660.953–1.2160.270
Sex4.1740.183–95.1800.340
CCIS1.4941.098–2.3110.0091.4361.156–1.8420.001
Diagnosis of ILDs3.389E + 1001.000
Serum LDH1.0040.994–1.0150.996
Serum KL-61.0000.999–1.0010.906
P/F ratio1.0040.982–1.0060.425
GGO score1.0600.897–1.2470.482

CCIS, Charlson Comorbidity Index Score; CI, confident interval; GGO, ground-glass opacity; ILD, interstitial lung disease; LDH, lactate dehydrogenase; KL-6, Krebs von den Lungen; P/F ratio, partial pressure of oxygen in arterial blood/fraction of inspired oxygen.