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Blood and Lymphatic Vessels of Human Lung in Health and Disease

Call for Papers

Besides their indispensable role in maintaining the interstitial compartment of the lung relatively dry to allow gas diffusion, the lymphatic vessels of the lung play a crucial role in inflammatory and immune responses, in cancer spreading, and in lung transplant. Lymphangiogenesis and lymphatic remodeling play controversial roles in a wide spectrum of lung diseases.

The importance of blood vessel formation and remodeling in the lung, both in health and in disease, is universally acknowledged. Blood vessel damage, remodeling, and/or angiogenesis occur in parallel with involvement of lymphatics in lung development and disease. However, the roles played by these phenomena are often no less controversial than those occurring in lymphatic vessels.

This special issue of the Canadian Respiratory Journal has the scope of gathering studies assessing distribution and functional relevance of blood and lymphatic vessels in the different compartments of the lung to unravel their role in the normal lung as well as in disease. Original articles and reviews on the topic are particularly encouraged. Priority will be given to original articles and reviews on clinical aspects.

Potential topics include but are not limited to the following:

  • Blood and lymphatic vessels in normal human lung: anatomy and structure
  • Pulmonary lymphatic ontogeny
  • Physiology of blood and pulmonary lymphatics
  • Angiogenesis, lymphangiogenesis, and vascular endothelial growth factors in lung diseases
  • Blood and lymphatic vessels in Interstitial Lung Disease, COPD, asthma, and other chronic pathologies of the lung
  • The lung interstitial compartment and the role of blood and lymphatic vessels in lung edema
  • Pulmonary lymphangiectasia
  • Pulmonary hypertension

Authors can submit their manuscripts through the Manuscript Tracking System at

Submission DeadlineFriday, 4 May 2018
Publication DateSeptember 2018

Papers are published upon acceptance, regardless of the Special Issue publication date.

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