Depression Following Thrombotic Cardiovascular Events in Elderly Medicare Beneficiaries: Risk of Morbidity and Mortality

Table 3

Time to event analyses.

Event	Variable	Hazard Ratio	95% CI		𝑃-value
Recurrent TCE
	Model 1
	Depression	1.09	0.96	1.23
	Model 2
	Depression	1.07	0.86	1.33
	Antidepressant	1.02	0.79	1.32
	Model 3
	Depression	1.02	0.85	1.22
	SSRI	1.13	0.89	1.43
	Model 4
	Depression	1.30	1.10	1.53
Death
	Model 1
	Depression	1.06	0.65	1.72
	Model 2
	Depression	1.73	0.85	3.51
	Antidepressant	0.52	0.21	1.33
	Model 3
	Depression	1.27	0.65	2.47
	SSRI	0.83	0.33	2.10

*All four models controlled for previous healthcare spending, age, race, gender, smoking status and history, poverty status, BMI, and baseline year.
^†Non-SSRI users are reference group in model 3; Nonantidepressant users are reference group in model 2.
^±Ties were handled with the Exact method.