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Cardiology Research and Practice
Volume 2010, Article ID 453851, 6 pages
http://dx.doi.org/10.4061/2010/453851
Review Article

Research Needed to Support Clinical Use of Biomarkers as Prognostic Indicators for Patients with Heart Failure

1Center for Chronic Disease Outcomes Research, VA Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA
2Department of Medicine, University of Minnesota, Minneapolis, MN 55455, USA
3Department of Cardiology, VA Medical Center, One Veterans Drive, Minneapolis, MN 55417, USA

Received 19 March 2010; Accepted 28 April 2010

Academic Editor: Hector Ventura

Copyright © 2010 Thomas S. Rector and Inder S. Anand. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Despite extensive research and numerous publications biomarkers have yet to fulfill their promise as prognostic indicators that can be widely used in the care of patients with heart failure. Specific clinical applications need to be identified for informative analyses of data that emphasize the most directly applicable measures of predictive performance.