Current Trends in Implantable Left Ventricular Assist Devices

Table 3

Most commonly used LVADs.

LVAD Types	HeartWare System	HeartMate II
Support duration; (patient years)	47.8 [20]	211 [5]
Outcome
(i) 30 days survival	98% [14]	96% [39]
(ii) 1-year survival	91% [14]	85% [39]
(iii) 2-year survival	—	70% [4]
Quality of life	+++ [14]	+++ [5, 10]
Approval
(i) BTT	Yes	Yes
(ii) DT	No, but on the way	Yes
Advantages	(i) Miniaturized pump	(i) Long-term support
	(ii) Implanted in the intrapericardial space	(ii) Destination therapy
	(iii) Indicated to support patients with BSA ≥ 1.2 m^2	(iii) Durability
	(iv) Right ventricular implantation	(iv) More than 1500 implants in Europe
	(v) Biventricular implantation
Disadvantages	(i) Driveline	(i) Require a pump pocket
	(a) Infection	(ii) Driveline
	(b) Breaking	(a) Infection
	(ii) Neurological dysfunction	(b) Breaking
	(iii) Hemolysis	(iii) Neurological dysfunction
		(iv) Bleedings

BTT: bridge to transplant; DT: destination therapy; BSA: body surface area.