TY - JOUR A2 - Shibata, Rei AU - Rao, Veena S. AU - Nagaraj, Radhika K. AU - Hebbagodi, Sridhara AU - Kadarinarasimhiah, Natesha B. AU - Kakkar, Vijay V. PY - 2011 DA - 2010/12/28 TI - Association of Inflammatory and Oxidative Stress Markers with Metabolic Syndrome in Asian Indians in India SP - 295976 VL - 2011 AB - Metabolic syndrome (MetS) is a primary risk factor for cardiovascular disease and is associated with a proinflammatory state. Here, we assessed the contribution of inflammatory and oxidative stress markers towards prediction of MetS. A total of 2316 individuals were recruited in Phase I of the Indian Atherosclerosis Research Study (IARS). Modified ATPIII guidelines were used for classification of subjects with MetS. Among the inflammatory and oxidative stress markers studied, levels of hsCRP (P<.0001), Neopterin (P=.036), and oxLDL (P<.0001) were significantly higher among subjects with MetS. Among the markers we tested, oxLDL stood out as a robust predictor of MetS in the IARS population (OR 4.956 95% CI 2.504–9.810; P<.0001) followed by hsCRP (OR 1.324 95% CI 1.070–1.638; P=.010). In conclusion, oxLDL is a candidate predictor for MetS in the Asian Indian population. SN - 2090-8016 UR - https://doi.org/10.4061/2011/295976 DO - 10.4061/2011/295976 JF - Cardiology Research and Practice PB - SAGE-Hindawi Access to Research KW - ER -