Acute Experimental Hyperthyroidism Does Not Affect Basal and Volume-Induced Atrial Natriuretic Peptide Secretion in Healthy Subjects

Table 4

Urinary electrolyte excretion before and after normal saline-induced plasma volume expansion at baseline and after T₃ administration.

Parameter	Before T3			After T3
	Before NS	After NS	Δ Response	Before NS	After NS	Δ Response
Aldo/creatinine, pmol/gr	113±45	115±51	55±192	168±190	124±96	9±89
Na/creatinine, mEq/gr	111±84	451±278^†	340±288	113±70	338±231^†	224±186
K/creatinine, mEq/gr	29±12	76±21 *	47±18	34±17	83±40 *	49±34
Ca/creatinine, mg/gr	167±56	285±161	119±190	224±84	248±152	23±179
P/creatinine, mg/gr	611±161	456±222	−155±120	597±223	345±191	−251±276
Mg/creatinine, mg/gr	49±24	109±101	60±112	83±47	72±42	−11±23

^∗𝑃<.01 compared to values before plasma volume expansion.
^†𝑃<.05 compared to values before plasma volume expansion.
NS: normal saline-induced plasma volume expansion.