Research Article

Early Heparin Administration Reduces Risk for Left Atrial Thrombus Formation during Atrial Fibrillation Ablation Procedures

Table 1

Patient characteristics.

AllGroup IGroup IIP
“late heparin”“early heparin”

n60 (100%)13 (21.7%)47 (78.3%)
Age (years)63.9 ± 11.356.6 ± 13.765.9 ± 9.9.01
Male gender (n)39 (65.0%)10 (76.9%)29 (61.7%).51
Paroxysmal AF (n)37 (61.7%)6 (46.2%)31 (65.9%).21

CHADS2 Score1.5 ± 1.11.5 ± 1.11.5 ± 1.1.92
 Hx CVA (n)10 (16.7%)4 (30.8%)6 (12.8%).2
 Hypertension (n)43 (71.7%)10 (76.9%)33 (70.2%).74
 Diabetes (n)6 (10%)06 (12.8%).32
CAD15 (25%)2 (15.4%)13 (27.7%).48

Echo-Parameters
 LV-EF (%)51.6 ± 8.951.2 ± 9.851.7 ± 8.8.74
 LA diameter (mm)45.5 ± 7.546.9 ± 9.045.1 ± 7.0.65
 LVEDD (mm)52.4 ± 8.751.4 ± 5.652.7 ± 9.4.98
 IVSd (mm)10.7 ± 1.410.8 ± 1.210.7 ± 1.5.61
 PWd (mm)10.7 ± 1.510.5 ± 1.910.8 ± 1.3.62
 LAA Vmax (cm/s)47.0 ± 16.341.2 ± 11.648.5 ± 17.1.24

Initial ACT (s)290.1 ± 67.8244.3 ± 40.7301.7 ± 68.7.002
Mean ACT (s)315.0 ± 43.7297.9 ± 40.9319.4 ± 43.7.11

AF: atrial fibrillation, Hx CVA: history of cerebrovascular event, CAD: coronary artery disease, LV-EF: left ventricular ejection fraction, LA: left atrium, LVEDD: left ventricular end-diastolic diameter, IVSd: interventricular septum thickness, PWd: posterior wall thickness, LAA Vmax: left atrial appendage maximal flow velocity, and ACT: activated clotting time.