Research Article
Early Heparin Administration Reduces Risk for Left Atrial Thrombus Formation during Atrial Fibrillation Ablation Procedures
Table 1
Patient characteristics.
| | All | Group I | Group II | P | “late heparin” | “early heparin” |
| n | 60 (100%) | 13 (21.7%) | 47 (78.3%) | | Age (years) | 63.9 ± 11.3 | 56.6 ± 13.7 | 65.9 ± 9.9 | .01 | Male gender (n) | 39 (65.0%) | 10 (76.9%) | 29 (61.7%) | .51 | Paroxysmal AF (n) | 37 (61.7%) | 6 (46.2%) | 31 (65.9%) | .21 |
| CHADS2 Score | 1.5 ± 1.1 | 1.5 ± 1.1 | 1.5 ± 1.1 | .92 | Hx CVA (n) | 10 (16.7%) | 4 (30.8%) | 6 (12.8%) | .2 | Hypertension (n) | 43 (71.7%) | 10 (76.9%) | 33 (70.2%) | .74 | Diabetes (n) | 6 (10%) | 0 | 6 (12.8%) | .32 | CAD | 15 (25%) | 2 (15.4%) | 13 (27.7%) | .48 |
| Echo-Parameters | | | | | LV-EF (%) | 51.6 ± 8.9 | 51.2 ± 9.8 | 51.7 ± 8.8 | .74 | LA diameter (mm) | 45.5 ± 7.5 | 46.9 ± 9.0 | 45.1 ± 7.0 | .65 | LVEDD (mm) | 52.4 ± 8.7 | 51.4 ± 5.6 | 52.7 ± 9.4 | .98 | IVSd (mm) | 10.7 ± 1.4 | 10.8 ± 1.2 | 10.7 ± 1.5 | .61 | PWd (mm) | 10.7 ± 1.5 | 10.5 ± 1.9 | 10.8 ± 1.3 | .62 | LAA Vmax (cm/s) | 47.0 ± 16.3 | 41.2 ± 11.6 | 48.5 ± 17.1 | .24 |
| Initial ACT (s) | 290.1 ± 67.8 | 244.3 ± 40.7 | 301.7 ± 68.7 | .002 | Mean ACT (s) | 315.0 ± 43.7 | 297.9 ± 40.9 | 319.4 ± 43.7 | .11 |
|
|
AF: atrial fibrillation, Hx CVA: history of cerebrovascular event, CAD: coronary artery disease, LV-EF: left ventricular ejection fraction, LA: left atrium, LVEDD: left ventricular end-diastolic diameter, IVSd: interventricular septum thickness, PWd: posterior wall thickness, LAA Vmax: left atrial appendage maximal flow velocity, and ACT: activated clotting time.
|