Review Article
Postmyocardial Infarct Remodeling and Heart Failure: Potential Contributions from Pro- and Antiaging Factors
Table 2
Summary of factors in Post-MI remodeling and heart failure.
| Parameter of remodeling | Effects on the heart |
| Changes in Myocytes | Myocyte hypertrophy | Fetal gene expression | Increased myocyte length | Decreased myocyte numbers | Increased myocyte cell death |
| Changes in cardiac morphology | Left ventricular dilatation | Increased extracellular matrix | Increased spherical shape | Increased wall thinning |
| Changes in left ventricular function | Increased oxygen consumption | Increased adrenergic response | Increased end systolic and diastolic dysfunction |
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