Strategies to Prevent Anthracycline-Related Congestive Heart Failure in Survivors of Childhood Cancer

Table 2

Children’s Oncology Group’s recommended frequency of echocardiogram or MUGA scan for childhood cancer survivors.^*

Age at treatment^†	Chest radiation	Anthracycline dose^††	Recommended frequency
<1 year old	Yes	Any	Every year
	No	<200 mg/m^2; ≥200 mg/m^2	Every 2 years; Every year
1–4 years old	Yes	Any	Every year
	No	<100 mg/m^2; ≥100 to <300 mg/m^2; ≥300 mg/m^2	Every 5 years; Every 2 years; Every year
≥5 years old	Yes	<300 mg/m^2; ≥300 mg/m^2	Every 2 years; Every year
	No	<200 mg/m^2; ≥200 to <300 mg/m^2; ≥300 mg/m^2	Every 5 years; Every 2 years; Every year
Any age with decrease in serial function			Every year

^*From the Children’s Oncology Group Long-Term FollowUp Guidelines for Survivors of Childhood, Adolescent, and Young Adult Cancers, Version 3.0, October 2008, used with permission.
^†Age at time of first cardiotoxic therapy.
^††Based on equivalent mg of doxorubicin/daunomycin.