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Cardiology Research and Practice
Volume 2012, Article ID 973974, 6 pages
Research Article

Health-Related Quality of Life among Patients with Coronary Artery Disease: A Post-Treatment Follow-Up Study in Iran

1Health Management Research Centre, Baqiyatallah University of Medical Sciences, 1435814717 Tahran, Iran
2Division of Health Economics, Department of Clinical Sciences-Malmö, Lund University, 20502 Malmö, Sweden
3Health Economics & Management, Institute of Economic Research, Lund University, 22007 Lund, Sweden
4Department of Health Management and Economics, School of Public Health, Tehran University of Medical Sciences, 141556447 Tehran, Iran
5School of Health Services and Information Management, Tehran University of Medical Sciences, 1995614111 Tehran, Iran
6Student Scientific Research Centre, Tehran University of Medical Sciences, Tehran, Iran
7Behin Pooyan Hootan Research Institute, 1483895931 Tehran, Iran

Received 22 December 2011; Revised 26 February 2012; Accepted 11 March 2012

Academic Editor: Lars S. Maier

Copyright © 2012 Shahram Tofighi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objective. To examine the changes in health-related quality of life (HRQoL) in patients with coronary artery disease (CAD) in terms of age, gender, and treatment strategy in Iran. Methods and Materials. Forty-nine patients responded to the Iranian version of the 36-item short form (SF-36) questionnaire to evaluate the HRQoL at first and third year after treatment. The paired and independent Wilcoxon rank-sum tests were used for within and between comparisons, respectively. Multivariate regression analysis was used to analyze the predictors of changes at HRQoL. Results. In general, during followup, the mental component summary scale improved, and the physical component summary scale declined. The results of multiple regression showed that the score at the first year post-treatment was the main predictor of HRQoL at follow up. Moreover, after adjusting for other covariates, receiving PTCA and being at older age were related to lower scores at followup, but these were not statistically significant in most cases. Conclusion. The HRQoL significantly changed from one to three years after treatment in patients with CAD. While, the physical health deteriorated during two-year follow up, mental health improved at the same time period. Generally, there were no significant differences at changes of HRQoL in terms of treatment, age, and gender.