Cardiology Research and Practice / 2014 / Article / Tab 1

Clinical Study

High-Sensitivity Troponin T: A Biomarker for Diuretic Response in Decompensated Heart Failure Patients

Table 1

Population characteristics and comparison of clinical variables, laboratory results, and medications between admission day (day 1) and day 3.

Age (yrs)76,0 ± 10,88
Male sex—%39
Diabetes mellitus—%45
Glycated HgB (%)7,02 ± 0,96
COPD—%17
Dementia—%12
Sleep apnea—%18
Noninvasive ventilation—%17
Ischemic heart disease—%50
Atrial fibrillation—%59
LV ejection fraction (%)43,46 ± 11,73
LV ejection fraction ≥40%—%68

Day 1Day 3 value

Body mass index (Kg/m2)29,44 ± 6,1728,35 ± 6,23<0,001
Heart rate (bpm)93,65 ± 24,3576,41 ± 11,96<0,001
SBP (mmHg)139,79 ± 25,86121,97 ± 16,2<0,001
Plasma creatinine (mg/dL)1,04 [0,89–1,31]1,06 0,85–1,400,082*
eGFR (mL/min/1,73 m2)58,0 [44,0–72,0]58,0 39,25–72,750,171*
Plasma urea (mg/dL)55,21 ± 20,8462,3 ± 25,470,001
Serum potassium (mmol/L)4,03 ± 0,514,04 ± 0,540,95
Serum sodium (mmol/L)140,54 ± 4,38140,68 ± 3,950,72
Hemoglobin (g/dL)12,43 ± 2,07
Albumin (mg/dL)3,68 ± 0,40
NTproBNP (pg/mL)2750 [1672–6032]1835 902–3837<0,001 *
hsTnT (ng/mL)0,033 [0,019–0,050]0,030 0,018–0,0510,039 *
IV furosemide—%10037<0,001 **
IV furosemide dose (mg/d)75,80 ± 21,5267,57 ± 25,540,001
Oral furosemide—%063
Oral furosemide dose (mg/d)074,6 ± 28,1
Furosemide dose reduction or oral route—%84
ACEi—%4461<0,001 **
Ramipril Eq. dose (mg/d)3,15 ± 2,043,36 ± 2,140,474
Beta-blocker—%3757<0,001 **
Bisoprolol Eq. dose (mg/d)3,01 ± 1,082,96 ± 1,890,474
Spironolactone—%50501**
Spironolactone dose (mg/d)94,50 ± 23,3162,74 ± 24,33<0,001

Continuous variables are presented as mean value ± standard deviation SD, value or median [interquartile range (IQR)], value. Categorical variables are presented as % of total (100 patients), value.
*Nonparametric paired sample test; **chi-square test.
COPD: chronic obstructive pulmonary disease; LV: left ventricular; eGFR: estimated glomerular filtration rate; NTproBNP: N-terminal probrain natriuretic peptide; hsTnT: high sensitivity troponin T; IV: intravenous; ACEi: angiotensin converting enzyme inhibitors.