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Cardiology Research and Practice
Volume 2015, Article ID 274892, 5 pages
http://dx.doi.org/10.1155/2015/274892
Research Article

Impact of Admission Glycosylated Hemoglobin A1c on Angiographic Characteristics and Short Term Clinical Outcomes of Nondiabetic Patients with Acute ST-Segment Elevation Myocardial Infarction

1Cardiology Department, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt
2Internal Medicine Department, Faculty of Medicine, Zagazig University, Zagazig 44519, Egypt
3Medical Biochemistry Department, Faculty of Medicine, Al-Azhar University, Cairo 11651, Egypt

Received 23 June 2015; Revised 10 October 2015; Accepted 16 November 2015

Academic Editor: Terrence D. Ruddy

Copyright © 2015 Islam El-sherbiny et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

We aimed to assess the predictive value of admission HbA1c level in nondiabetic patients presented by acute STEMI, on outcome of PCI and short term outcome of adverse cardiac events. Methods. 60 nondiabetic patients were admitted to Cardiology Department, Zagazig University Hospital, with acute STMI: 27 patients with HbA1c levels of 4.5% to 6.4% (group 1), 17 patients with HbA1c levels of 6.5% to 8.5% (group 2), and 16 patients with HbA1c levels higher than 8.5% (group 3). Either invasive intervention was done at admission by (pPCI) or coronary angiography was done within month (3–28 days) from taking thrombolytic. Participants were followed up for 6 months. Results. There was significant difference among different groups of HbA1c as regards the number of diseased vessels, severity of CAD lesions ( value < 0.01), and TIMI flow grades ( value < 0.05). There was significant difference among different groups as regards the adverse cardiac events on short term follow-up period ( value < 0.05). Conclusion. The present study showed that admission higher HbA1c level in patients presented by acute STEMI is associated with more severe CAD, lower rate of complete revascularization, and higher incidence of adverse cardiac events.