Impact of Lifestyle Intervention on HDL-Induced eNOS Activation and Cholesterol Efflux Capacity in Obese Adolescent

Figure 1

Impact of lifestyle intervention program on HDL-mediated eNOS phosphorylation. Ten months of intervention increases HDL-mediated eNOS-Ser1177 phosphorylation in the intervention group when analyzed over time (a) or compared to usual care group (UC) (b). No change in HDL-mediated eNOS-Ser¹¹⁷⁷ phosphorylation occurs in UC (c). Phosphorylation of the eNOS-Thr⁴⁹⁵ residue was not affected by the intervention program when compared to UC (d).

(a)

(b)

(c)

(d)