Assessment of the Protective Role of Prenatal Zinc versus Insulin Supplementation on Fetal Cardiac Damage Induced by Maternal Diabetes in Rat Using Caspase-3 and KI67 Immunohistochemical Stains

Table 4

Percentage of frequency distribution of vacuolar degenerative changes in the different groups.

Parameter	Group
	C	STZ-DM	STZ-DM + Zn	STZ-DM + In
No change (%)	95	0	2	2
Mild change (%)	5	5	80	25
Moderate change (%)	0	15	13	55
Marked change (%)	0	80	5	18
Total (%)	100	100	100	100

Chi-square 637.9.
value < 0.00001.
C: control group, STZ-DM: streptozotocin-induced diabetic group, STZ-DM + In: streptozotocin-induced diabetic treated with insulin group, and STZ-DM + Zn: streptozotocin-induced diabetic treated with Zn group.
, compared to the control group and compared to the STZ-DM group.