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Cardiology Research and Practice
Volume 2016, Article ID 8047340, 5 pages
http://dx.doi.org/10.1155/2016/8047340
Research Article

Correlation between Doppler, Manual Morphometry, and Histopathology Based Morphometry of Radial Artery as a Conduit in Coronary Artery Bypass Grafting

1Department of Cardiothoracic Surgery, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India
2Department of Cardiology, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India
3Department of Cardiac Anesthesiology, National Heart Institute, 49-50 Community Centre, East of Kailash, New Delhi 110065, India
4Department of Pathology, All India Institute of Medical Sciences, New Delhi 110029, India

Received 27 October 2015; Revised 28 January 2016; Accepted 8 February 2016

Academic Editor: Michael S. Wolin

Copyright © 2016 Om Prakash Yadava et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. Long-term graft patency is the major factor impacting survival after coronary artery bypass grafting. Arteries are superior in this regard. Radial artery is considered the second best conduit after internal mammary artery. Several studies have shown excellent radial artery patency. We evaluated the morphologic characteristics of radial artery by three modalities, (i) preoperative Doppler ultrasound, (ii) intraoperative manual morphometry, and (iii) postoperative histology-based morphometry, and compared these with the aim of validating Doppler as a noninvasive test of choice for preoperative assessment of radial artery. Methods. This was a prospective study involving 100 patients undergoing coronary artery bypass grafting in which radial artery was used. The radial artery was assessed using preoperative Doppler ultrasound studies, intraoperative morphometry, and postoperative histopathology and morphometry. The morphometric measurements included (i) luminal diameter, (ii) intimal and medial thickness, and (iii) intima-media thickness ratio. Results. Using Bland-Altman plots, there was a 95% limit of agreement between the preoperative Doppler measurements and the postoperative histopathology and morphometry. Conclusion. Doppler ultrasound is an accurate screening test for evaluation of radial artery, in terms of intimal/medial thickness and luminal diameter as a conduit in coronary artery bypass grafting and has been validated by both morphometric and histopathology based studies.