The Relationship between Body Mass Index and the Severity of Coronary Artery Disease in Patients Referred for Coronary Angiography
Table 1
Baseline characteristics of study subjects undergoing coronary angiography in relation to BMI category and Duke Jeopardy Score (DJS) based on coronary angiographic findings in relation to BMI category ().
Variable
Normal
Overweight
Obese
Weight (kgs ± SD)
0.000
BMI (mean ± SD)
0.000
Age, years (mean ± SD)
59.7 ± 10.2
0.000
Male sex
744/1297 (57.4%)
2081/3072 (67.7%)
2249/3710 (60.6%)
0.000
HTN
735/1297 (56.7%)
1870/3069 (60.9%)
2629/3704 (71.0%)
0.000
Hyperlipidemia
991/1297 (76.4%)
2433/3068 (79.3%)
3022/3706 (81.5%)
0.000
Family history of premature
730/1295 (56.4%)
1925/3063 (62.8%)
2421/3695 (65.5%)
0.000
Current/former smoker
889/1295 (68.6%)
2105/3060 (68.8%)
2557/3693 (69.2%)
0.890
Diabetes
203/1297 (15.7%)
638/3069 (20.8%)
1279/3708 (34.5%)
0.000
Renal insufficiency
67/1296 (5.2%)
124/3069 (4.0%)
130/3705 (3.5%)
0.030
Dialysis
16/1296 (1.2%)
15/3069 (0.5%)
19/3705 (0.5%)
0.009
CRF
38/1296 (2.9%)
69/3069 (2.2%)
75/3705 (2.0%)
0.166
Malignancy
67/1296 (5.2%)
132/3069 (4.3%)
153/3705 (4.1%)
0.282
COPD
210/1297 (16.2%)
398/3069 (13.0%)
697/3705 (18.8%)
0.000
PVD
91/1297 (7.0%)
131/3069 (4.3%)
139/3705 (3.8%)
0.000
CHF
25/1296 (1.9%)
54/3069 (1.8%)
81/3705 (2.2%)
0.450
CVD
90/1296 (6.9%)
163/3069 (5.3%)
204/3705 (5.5%)
0.088
ACS ()
842 (19.3)
1709 (39.2)
1808 (41.5)
STEMI
243 (28.9)
426 (39.2)
419 (38.5)
0.000
Non-STEMI
382 (45.4)
791 (46.3)
850 (47.0)
Unstable angina
217 (25.8)
492 (28.8)
539 (29.8)
LV grade
I (>50%)
1067/1286 (83.0%)
2557/3033 (84.3%)
3154/3668 (86.0%)
0.003
II (35–50%)
136/1286 (10.6%)
334/3033 (11.0%)
353/3668 (9.6%)
III (20–34%)
52/1286 (4.0%)
110/3033 (3.6%)
110/3668 (3.0%)
IV (<20%)
31/1286 (2.4%)
32/3033 (1.1%)
51/3668 (1.4%)
DJS
≥2
771/1297 (59.4)
1875/3072 (61.0)
2023/3710 (54.5)
0.000
≥4
542/1297 (41.8)
1229/3072 (40.0)
1303/3710 (35.1)
0.000
≥6
424/1297 (32.7)
966/3072 (31.4)
992/3710 (26.7)
0.000
≥8
248/1297 (19.1)
56/3072 (18.5)
593/3710 (16.0)
0.006
≥10
162/1297 (12.5)
369/3072 (12.0)
395/3710 (10.6)
0.096
12
91/1297 (7.0)
198/3072 (6.4)
188/3710 (5.1)
0.010
Medications at time of referral
Aspirin
1162/1297 (89.6)
2780/3071 (90.5)
3294/3709 (88.8)
0.071
Beta blockers
990/1295 (76.4)
2313/3071 (75.3)
2806/3709 (75.7)
0.729
ACE inhibitors
514/1295 (39.7)
1279/3071 (41.6)
1651/3708 (44.5)
0.004
ARB antagonists
116/1295 (9.0)
357/3071 (11.6)
663/3708 (17.9)
0.000
CCB
161/1295 (12.4)
446/3071 (14.5)
619/3708 (16.7)
0.000
Statin therapy
972/1296 (75.0)
2382/3071 (77.6)
2897/3709 (78.1)
0.068
LA nitrates
264/1295 (20.4)
629/3071 (20.5)
769/3709 (20.7)
0.951
Ticlopidine/clopidogrel
800/1297 (61.7)
1603/3071 (52.2)
1699/3708 (45.8)
0.000
Values are means ± SD or % (). ACE = angiotensin converting enzyme; ACS = acute coronary syndrome; ARB = angiotensin receptor blocker; CAD = coronary artery disease; CCB = calcium channel blockers; CHF = congestive heart failure; COPD = chronic obstructive pulmonary disease; CRF = chronic renal failure; CVD = cerebrovascular disease; DJS = Duke Jeopardy Score; HTN = hypertension; LA = long-acting; PVD = peripheral vascular disease. history of CAD is positive if the patient has/had any direct blood relative (parent, siblings, and children) who have been diagnosed with angina, MI, or sudden cardiac death before age of 55 years. Note. DJS, Duke Jeopardy Score, is a score from 0 to 12 which estimates the amount of myocardium at risk on the basis of particular location of stenosis. A score of 0 is indicative of a normal angiogram or noncritical (<70%) stenosis in any of the coronary arteries. A score of 0 was assigned to 526 (40.6%) normal weight patients, 1197 (39.0%) overweight patients, and 1687 (45.5%) obese patients. value for chi-square for categorical variables or ANOVA for continuous variables.
