Radiofrequency Ablation versus Cryoablation in the Treatment of Paroxysmal Atrial Fibrillation: A Meta-Analysis

Table 3

Reported postoperative complications after cryoballoon ablation versus radiofrequency ablation.

Study	Cryoballoon ablation		Radiofrequency ablation
	Complication	Number of patients ()	Complication	Number of patients ()
Pérez-Castellano et al. [13]	Hemoptysis	1	Right femoral arteriovenous fistula	1
Herrera Siklódy et al. [15]	Phrenic nerve injury	2
	Femoral pseudoaneurysm	1
	Groin hematoma	1
Hunter et al. [16]	Phrenic nerve injury	4	Tamponade	1
			Hematoma	1
			Asymptomatic pulmonary vein stenosis	1
			Dressler’s syndrome	1
Kuck et al. [6]	Phrenic nerve injury	10	Groin site complication	16
	Groin site complication	7	Cardiac tamponade/pericardial effusion	5
	Other, nonarrhythmia complications	3	Pulmonary complication	4
	Pulmonary complication	2	Transient neurological complication	3
	Cardiac tamponade/pericardial effusion	1	Dyspnea	2
	Transient neurological complication	1	Gastrointestinal complication	2
	Dyspnea	1	Contrast media reaction	1
	Anxiety	1	Contusion	1
	Esophageal ulcer	1	Hematuria	1
	Gastrointestinal complication	1	Local edema	1
Luik et al. [5]	Phrenic nerve injury	9	Vascular	5
	Vascular	8	Pericardial effusion	3
	Pericardial effusion	2
Malmborg et al. [18]	Groin hematoma	2	Groin hematoma	1
	Phrenic nerve injury	2
Pokushalov et al. [14]	Phrenic nerve injury	3
Total patients		65		50

As per the study, groin site complications included vascular pseudoaneurysm, arteriovenous fistula, device-related infection, hematoma, puncture site hemorrhage, and groin pain. As per the study, other cardiac complications included atrial septal defects, coronary artery disease, and pericarditis.