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Cardiology Research and Practice
Volume 2018 (2018), Article ID 6572785, 8 pages
Research Article

Cardiovascular Risk Assessment in a Cohort of Newly Diagnosed Patients with Obstructive Sleep Apnea Syndrome

1MSc Program in Sleep Medicine, Medical School, Democritus University of Thrace, Alexandroupolis, Greece
2Department of Pneumonology, Medical School, Democritus University of Thrace, Alexandroupolis, Greece
3Laboratory of Hygiene and Environmental Protection, Medical School, Democritus University of Thrace, Alexandroupolis, Greece
4Division of Immunology, Biomedical Sciences Research Center “Alexander Fleming”, Athens, Greece
51st Cardiology Department, General Hospital of Nikea “Agios Panteleimon”, Nikea, Greece

Correspondence should be addressed to Athanasios Voulgaris

Received 30 October 2017; Accepted 24 January 2018; Published 8 March 2018

Academic Editor: Anne Knowlton

Copyright © 2018 Kostas Archontogeorgis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Objectives. Obstructive sleep apnea syndrome (OSAS) is associated with increased cardiovascular morbidity and mortality. The aim of this study was to assess whether the 10-year risk for cardiovascular disease in newly diagnosed patients with OSAS is increased. Materials and Methods. Recently diagnosed, with polysomnography, consecutive OSAS patients were included. The Systematic Coronary Risk Evaluation (SCORE) and the Framingham Risk Score (FRS) were used to estimate the 10-year risk for cardiovascular disease. Results. Totally, 393 individuals (73.3% males), scheduled to undergo a polysomnographic study with symptoms indicative of OSAS, were enrolled. According to apnea-hypopnea index (AHI), subjects were divided in four groups: mild OSAS (AHI 5–14.9/h) was diagnosed in 91 patients (23.2%), moderate OSAS (AHI 15–29.9/h) in 58 patients (14.8%), severe OSAS (AHI > 30/h) in 167 patients (42.5%), while 77 individuals (19.6%) had an AHI < 5/h and served as controls. Increased severity of OSAS was associated with increased SCORE and FRS values . More specifically, a significant correlation was observed both between AHI and SCORE and AHI and FRS values . Furthermore, a negative correlation was observed between FRS values and sleep efficiency . Conclusions. The 10-year risk for cardiovascular morbidity and mortality seems to increase with severity of OSAS. Physicians should bear this finding in mind, in order to seek for and consecutively eliminate risk factors for cardiovascular disease and to prevent future cardiovascular events in OSAS patients.