Research Article
Cardiovascular Risk Assessment in a Cohort of Newly Diagnosed Patients with Obstructive Sleep Apnea Syndrome
Table 3
Comparison of the laboratory measurements between controls and obstructive sleep apnea syndrome (OSAS) patients.
| | | Controls | Mild OSAS | Moderate OSAS | Severe OSAS | Controls versus mild OSAS | Controls versus moderate OSAS | Controls versus severe OSAS | Mild versus moderate OSAS | Mild versus severe OSAS | Moderate versus severe OSAS |
| | FEV1 (% predicted) | 99.3 ± 16.4 | 100.2 ± 18.3 | 100.4 ± 18.1 | 92.5 ± 21.9 | 0.787 | 0.786 | 0.051 | 0.964 | 0.028 | 0.086 | | FVC (% predicted) | 94.4 ± 15.3 | 94.5 ± 15.5 | 94.7 ± 16.3 | 86.7 ± 20.8 | 0.963 | 0.929 | 0.022 | 0.958 | 0.017 | 0.067 | | FEV1/FVC (%) | 84.9 ± 8.6 | 83.9 ± 9.1 | 86.1 ± 12.3 | 83.1 ± 12 | 0.553 | 0.616 | 0.341 | 0.356 | 0.662 | 0.256 | | pO2 (mmHg) | 82.2 ± 14.2 | 82.7 ± 11.9 | 82.5 ± 11.6 | 76.4 ± 11 | 0.830 | 0.902 | 0.008 | 0.946 | 0.001 | 0.008 | | pCO2 (mmHg) | 40.1 ± 3.4 | 40.3 ± 3.6 | 40.1 ± 3.7 | 41.7 ± 4 | 0.848 | 0.923 | 0.020 | 0.800 | 0.033 | 0.045 | | SBP (mmHg) | 119.6 ± 14.3 | 125.9 ± 15.9 | 129.4 ± 15.5 | 134.8 ± 16.6 | 0.008 | <0.001 | <0.001 | 0.183 | <0.001 | 0.032 | | DBP (mmHg) | 77.7 ± 9.9 | 80.5 ± 8.7 | 80.1 ± 7.4 | 84 ± 9.5 | 0.052 | 0.105 | <0.001 | 0.776 | 0.004 | 0.002 | | Cholesterol (mg/dL) | 214.2 ± 45.9 | 210.7 ± 37.8 | 222.8 ± 47 | 229.1 ± 39.9 | 0.591 | 0.288 | 0.010 | 0.085 | <0.001 | 0.317 | | Triglycerides (mg/dL) | 130 (89–165) | 162 (110.5–230) | 144 (74–180.5) | 120 (94–195) | 0.049 | 0.712 | 0.467 | 0.144 | 0.148 | 0.663 | | LDL-C (mg/dL) | 131.3 ± 35.2 | 131.6 ± 30.8 | 141.9 ± 39.3 | 129.9 ± 35.8 | 0.964 | 0.269 | 0.853 | 0.269 | 0.814 | 0.150 | | HDL-C (mg/dL) | 50 ± 12.4 | 49.5 ± 14 | 50.9 ± 12.1 | 43.8 ± 10.4 | 0.830 | 0.649 | <0.001 | 0.525 | <0.001 | <0.001 | | Glucose (mg/dL) | 101.2 ± 21.5 | 103.8 ± 22.3 | 98.3 ± 20.2 | 107.1 ± 21.8 | 0.671 | 0.395 | 0.174 | 0.234 | 0.361 | 0.047 | | SCORE | 0 (0–1) | 1 (0–2) | 1 (0–3) | 1.5 (1–3) | 0.001 | <0.001 | <0.001 | 0.049 | <0.001 | 0.023 | | FRS | 3 (1–5) | 4 (1.5–7) | 10 (2.5–13.5) | 12 (5–15) | 0.004 | <0.001 | <0.001 | 0.030 | <0.001 | 0.008 |
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DBP: diastolic blood pressure; FEV1: forced expiratory volume in 1st sec; FRS: Framingham Risk Score; FVC: forced vital capacity; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; pCO2: partial carbon dioxide pressure; pO2: partial oxygen pressure; SCORE: Systematic Coronary Risk Evaluation; SBP: systolic blood pressure.
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