Effects of Cardiac Hypertrophy, Diabetes, Aging, and Pregnancy on the Cardioprotective Effects of Postconditioning in Male and Female Rats

Table 2

Effects of ischemia-reperfusion and PPC on cardiac enzymes levels.

Treatment	CK IU/L	value	LDH IU/L	value
Ctr male	21.32 ± 1.84	—	20.73 ± 1.37	—
Ctr male + PPC	9.41 ± 1.87	0.001	7.94 ± 1.83	0.001
Ctr old male	21.13 ± 1.12	—	18.62 ± 2.10	—
Old male + PPC	20.23 ± 1.43	0.231	18.42 ± 2.02	0.411
Ctr female	20.13 ± 1.82	—	18.93 ± 1.11	—
Ctr female + PPC	10.21 ± 1.71	0.001	9.95 ± 1.64	0.001
Ctr old female	20.13 ± 1.86	—	16.47 ± 1.82	—
Old female + PPC	10.53 ± 1.24	0.001	9.03 ± 1.65	0.001
Ctr male	23.41 ± 2.13	—	19.21 ± 1.98	—
Ctr male + PPC	10.23 ± 1.43	0.001	8.11 ± 2.13	0.001
Ctr LVH male	23.54 ± 2.63	—	16.22 ± 1.43	—
LVH male + PPC	21.39 ± 2.02	0.315	17.53 ± 1.45	0.314
Ctr female	20.85 ± 1.93	—	17.97 ± 1.36	—
Ctr female + PPC	10.98 ± 1.61	0.001	9.14 ± 1.82	0.001
Ctr LVH female	22.10 ± 1.83	—	16.31 ± 1.92	—
LVH female + PPC	9.14 ± 1.19	0.001	10.63 ± 1.92	0.01
Ctr diabetic male	23.75 ± 2.13	—	17.52 ± 1.61	—
Diabetic male + PPC	21.72 ± 1.71	0.524	19.27 ± 2.13	0.243
Ctr diabetic female	20.63 ± 2.85	—	18.92 ± 1.62	—
Diabetic female + PPC	21.31 ± 1.86	0.463	18.26 ± 1.23	0.217
Ctr female 19 GD	20.42 ± 1.66	—	16.24 ± 1.23	—
Female 19 GD + PPC	9.92 ± 1.12	0.001	8.31 ± 1.14	0.001
Ctr female 21 GD	21.33 ± 1.62	—	17.24 ± 1.38	—
Female 21 GD + PPC	9.87 ± 1.95	0.001	8.05 ± 1.23	0.001

CK: creatine kinase; LDH: lactate dehydrogenase; Ctr: control; PPC: pacing postconditioning; LVH: left ventricle hypertrophy; GD: gestation day. compared to the respective control.