Fibrinogen-to-Albumin Ratio Predicts Contrast-Induced Nephropathy in Patients after Emergency Percutaneous Coronary Intervention
Table 1
Baseline clinical features in patients with and without CIN.
CIN (−) (n = 536)
CIN (+) (n = 29)
value
Demographics
Age, years
62.80 ± 12.08
72.90 ± 11.33
<0.001
Age >75 years, n (%)
83 (15.5%)
14 (48.3%)
<0.001
Sex, female, n (%)
70 (13.1%)
1 (3.4%)
0.158
Medical history
Smoker
318 (59.3%)
21 (72.4%)
0.161
Prior PCI, n (%)
17 (3.2%)
1 (3.4%)
1.000
Hypertension, n (%)
309 (57.6%)
17 (58.6%)
0.918
Diabetes, n (%)
138 (25.7%)
11 (37.9%)
0.147
Laboratory measurements
Albumin, g/L
39.79 ± 3.95
37.14 ± 5.21
0.012
Creatinine, mg/dl
0.85 ± 0.26
1.14 ± 0.61
0.017
SCr >1.5 mg/dl, n (%)
14 (2.6%)
5 (17.2%)
0.002
WBC, 109/l
12.10 ± 3.86
13.54 ± 4.49
0.053
Hemoglobin, g/l
140.86 ± 15.72
131.24 ± 26.17
0.06
Hematocrit
0.56 ± 2.48
1.75 ± 7.32
0.392
Neutrophil, 109/l
9.83 ± 3.77
11.50 ± 4.06
0.021
Cholesterol, mmol/l
4.85 ± 1.14
4.44 ± 1.12
0.062
Triglyceride, mmol/l
1.54 ± 1.17
1.12 ± 0.44
0.057
Low-density lipoprotein, mmol/l
3.28 ± 1.01
2.92 ± 1.07
0.059
Fibrinogen, g/l
3.51 ± 0.94
4.14 ± 0.96
<0.001
LVEF <45%, n (%)
37 (6.9%)
10 (34.5%)
<0.001
Procedure performed
Perioperative hypotension, n (%)
183 (34.1%)
20 (69.0%)
<0.001
Contrast volume >200 ml, n (%)
376 (70.1%)
23 (79.3%)
0.291
IABP
10 (1.9%)
4 (13.8%)
0.004
Data are presented as the means ± standard deviations or as numbers and percentages. CIN—contrast-induced nephropathy; PCI—percutaneous coronary intervention; SCr—serum creatinine; WBC—white blood cell; LVEF—left ventricular ejection fraction; IABP—intraaortic balloon pump.