Research Article

Fibrinogen-to-Albumin Ratio Predicts Contrast-Induced Nephropathy in Patients after Emergency Percutaneous Coronary Intervention

Table 1

Baseline clinical features in patients with and without CIN.

CIN (−) (n = 536)CIN (+) (n = 29) value

Demographics
 Age, years62.80 ± 12.0872.90 ± 11.33<0.001
 Age >75 years, n (%)83 (15.5%)14 (48.3%)<0.001
 Sex, female, n (%)70 (13.1%)1 (3.4%)0.158
Medical history
 Smoker318 (59.3%)21 (72.4%)0.161
 Prior PCI, n (%)17 (3.2%)1 (3.4%)1.000
 Hypertension, n (%)309 (57.6%)17 (58.6%)0.918
 Diabetes, n (%)138 (25.7%)11 (37.9%)0.147
Laboratory measurements
 Albumin, g/L39.79 ± 3.9537.14 ± 5.210.012
 Creatinine, mg/dl0.85 ± 0.261.14 ± 0.610.017
 SCr >1.5 mg/dl, n (%)14 (2.6%)5 (17.2%)0.002
 WBC, 109/l12.10 ± 3.8613.54 ± 4.490.053
 Hemoglobin, g/l140.86 ± 15.72131.24 ± 26.170.06
 Hematocrit0.56 ± 2.481.75 ± 7.320.392
 Neutrophil, 109/l9.83 ± 3.7711.50 ± 4.060.021
 Cholesterol, mmol/l4.85 ± 1.144.44 ± 1.120.062
 Triglyceride, mmol/l1.54 ± 1.171.12 ± 0.440.057
 Low-density lipoprotein, mmol/l3.28 ± 1.012.92 ± 1.070.059
 Fibrinogen, g/l3.51 ± 0.944.14 ± 0.96<0.001
 LVEF <45%, n (%)37 (6.9%)10 (34.5%)<0.001
Procedure performed
 Perioperative hypotension, n (%)183 (34.1%)20 (69.0%)<0.001
 Contrast volume >200 ml, n (%)376 (70.1%)23 (79.3%)0.291
 IABP10 (1.9%)4 (13.8%)0.004

Data are presented as the means ± standard deviations or as numbers and percentages. CIN—contrast-induced nephropathy; PCI—percutaneous coronary intervention; SCr—serum creatinine; WBC—white blood cell; LVEF—left ventricular ejection fraction; IABP—intraaortic balloon pump.