Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility

Table 3

Comparison of SIRT1, eNOS protein, TAS, TOS, and OSI levels in patients with STEMI and control subjects.

	STEMI group	Control group
SIRT 1 protein (ng/ml)	1.24 ± 1.07	0.7 ± 0.46	<0.001
eNOS protein (pg/ml)	274.6 ± 313.9	505.9 ± 571.0	0.001
TAS (mmol trolox equiv./L)	1.88 ± 0.34	1.84 ± 0.32	ns
TOS (mmol H2O2 equiv./L)	13.9 ± 7.4	12.9 ± 5.7	ns
OSI (arbitrary units)	0.78 ± 0.72	0.72 ± 0.32	ns

Statistical evaluation by Student’s t-test. The results are shown as mean ± standard deviation (SD). . SIRT 1, sirtuin 1; eNOS, endothelial nitric oxide synthase; TAS, total antioxidant status; TOS, total oxidant status; OSI, oxidative stress index; STEMI, ST-elevation myocardial infarction.