Cardiology Research and Practice / 2019 / Article / Tab 3

Research Article

Premature Myocardial Infarction: Genetic Variations in SIRT1 Affect Disease Susceptibility

Table 3

Comparison of SIRT1, eNOS protein, TAS, TOS, and OSI levels in patients with STEMI and control subjects.

STEMI groupControl group

SIRT 1 protein (ng/ml)1.24 ± 1.070.7 ± 0.46<0.001
eNOS protein (pg/ml)274.6 ± 313.9505.9 ± 571.00.001
TAS (mmol trolox equiv./L)1.88 ± 0.341.84 ± 0.32ns
TOS (mmol H2O2 equiv./L)13.9 ± 7.412.9 ± 5.7ns
OSI (arbitrary units)0.78 ± 0.720.72 ± 0.32ns

Statistical evaluation by Student’s t-test. The results are shown as mean ± standard deviation (SD). . SIRT 1, sirtuin 1; eNOS, endothelial nitric oxide synthase; TAS, total antioxidant status; TOS, total oxidant status; OSI, oxidative stress index; STEMI, ST-elevation myocardial infarction.

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