Effects of Ivabradine on Residual Myocardial Ischemia after PCI Evaluated by Stress Echocardiography

Table 3

Stress echocardiography at randomization time (T1).

	IG pts		CG pts
	T1		T1		value
	Rest	Peak exercise	Rest	Peak exercise	Rest	Peak exercise
Mean heart rate (bpm)	71.1 ± 5.3	126.6 ± 11.1	68.7 ± 8.1	118.4 ± 17	0.36	0.14
Max HR (bpm)	75.4 ± 8.3		68.3 ± 12.2		0.08
Chronotropic reserve (bpm)	53 ± 9		46 ± 14		0.12
Exercise time	8′:15″±18.9″		7′:50″±47″		0.12
METS	9.0 ± 0.3		8.6 ± 0.7		0.06
Maximal test (%)	14%		14%		1
DP	22255 ± 4504		19668 ± 4462		0.14
ΔP	13.5 ± 3.5		11.11 ± 3.3		0.07
Peak power (Watt)	121.4 ± 9.4		112.5 ± 13.7		0.06
Symptoms (%)	57.1		42.8		0.70
ECG alterations (%)	57.1		71		0.70
Mean rest LVEF (%)	51.8 ± 2.9		51.7 ± 8.5		0.97
LVEDD (mm)	48.1 ± 2.5	48.6 ± 2.1	49.9 ± 4.9	49.3 ± 4.2	0.98	0.97
LVEDV (ml)	133.6 ± 22.2	125.3 ± 19.2	126.9 ± 45.8	112.4 ± 39.5	0.62	0.28
LVESV (ml)	64.6 ± 12.1	57.8 ± 9.7	65.9 ± 32.4	54.7 ± 26.9	0.88	0.68
E wave (cm/sec)	63.3 ± 10.2	84.1 ± 6.6	70.4 ± 22.3	98.1 ± 34.6	0.28	0.14
A wave (cm/sec)	67.1 ± 15.4	83.6 ± 24.6	74.6 ± 14.0	95.6 ± 9.0	0.18	0.09
E/A	0.98 ± 0.23	1.13 ± 0.58	0.95 ± 0.3	1.01 ± 0.3	0.76	0.49
E′ wave (cm/sec)	8 ± 2.2	9.8 ± 1.55	7.0 ± 2.2	10.7 ± 3.5	0.24	0.38
E/E′	8.3 ± 1.91	8.7 ± 1.57	10.4 ± 3.4	9.7 ± 3.0	0.30	0.27
ET correct for HR (s)	0.47 ± 0.04	0.64 ± 0.14	0.45 ± 0.11	0.57 ± 0.11	0.52	0.15
DT correct for HR (s)	0.53 ± 0.03	0.74 ± 0.07	0.60 ± 0.09	0.67 ± 0.18	0.01	0.2
TP	14709 ± 5731		10916 ± 4451		0.06

DP = double product; TP = triple product; LVEF = left ventricular ejection fraction; LVEDD = left ventricular end-diastolic diameter; ET = ejection time; DT = diastolic time; LVEDV = left ventricular end-diastolic volume; LVESV = left ventricular end-systolic volume.