Reduced Albuminuria and Potassemia Indicate Early Renal Repair Processes after Resynchronization Therapy in Cardiorenal Syndrome Type 2

Table 3

Selected laboratory data from the entire group of patients with chronic heart failure prior to and 48 hours following CRT implantation (n = 64).

Variable	Before CRT median (lower-upper quartile)	48 hours after CRT median (lower-upper quartile)	R	^#
sCR (mg/dL)	1.11 (0.925–1.35)	1,22 (0.95–1.95)	0.78	0.1846
eGFR CKD-EPI (ml/min/1,73 m^2)	65 (50.5–79)	62 (50–78)	0.78	0.1341
uAlb (mg/dL)	16.89 (6.42–55.7)	11.305 (5.24–32.61)	0.62	0.0096
uACR (mg/g)	18.37 (6.44–68.6)	10.52 (5.81–32.66)	0.63	0.0492
uNGAL (ng/mL)	14.75 (8.8–32)	14.25 (7.7–32.3)	0.48	0.65
uNCR	15.11 (8.57–29.38)	14.47 (9.73–28.245)	0.55	0.0753
uCr (mg/dL)	0.998 (0.546–1.594)	1.262 (0.614–1.749)	0.40	0.2617
Hb (g/dL)	13.4 (12.2–14.6)	13.2 (12.3–14.4)	0.87	0.0034
HCT (%)	39.8 (38.1–43.5)	39.1 (36.6–42.6)	0.82	0.0333
RBC, millions per K/µL	4.47 (4.14–4.83)	4.39 (4.09–4.83)	0.79	0.0286
WBC, thousands per K/µL	6.6 (5.45–8.85)	7.08 (6.24–8.85)	0.76	0.0758
PK, thousands per K/µL	196 (160–238)	172 (145–221)	0.90	<0.0001
Na (mmol/L)	136.5 (134–139)	136 (134–138)	0.67	0.2343
K (mmol/L)	4.4 (4.1–4.7)	4.1 (3.9–4.5)	0.31	0.0002
CRP (mg/L)	3.65 (1.7–8.4)	14,9 (10.5––25)	0,71	0.1798

^#Student’s t-tests for dependent pairs to compare the significance of the difference in levels of a given parameter between points 0 and 48. Abbreviations: sCr-creatinine serum; eGFR CKD-EPI, estimated glomerular filtration rate calculated using Chronic Kidney Disease Epidemiology Collaboration; uAlb, urinary albumin concentration in a single morning sample of urine; uACR, urinary albumin to creatinine ratio; uNGAL, lipocalin associated with neutrophil gelatinase in a single morning sample of urine; uNCR, urinary NGAL to creatinine ratio; uCr, urea creatinine; Hb, hemoglobin; HCT, hematocrit; RBC, red blood cell count; WBC, white blood cell count; PK, platelet count; Na, sodium; K, potassium; CRP, C-reactive protein.